Inhibition activity of water hyacinth (Eichhornia crassipes) leaf extract against Prevotella intermedia

Background: Water hyacinth is a plant that grows in freshwater, commonly found Indonesia. leaf extract contains antimicrobial bioactive components such as tannins, flavonoids, alkaloids, and terpenoids. Prevotella intermedia one of the bacteria cause periodontal disease. increases subgingival plaques patients with disease exacerbated by hormonal changes. Therefore, water may affect growth intermedia. Objective: To determine inhibition activity on Method: This research was conducted vitro using extract. Which generated serial dilution method to obtain Minimum Inhibitory Concentrations (MIC) 90% Bactericidal (MBC) 99,9%. The concentrations were obtained at 100%, 50%, 25%, 12.5 %, 6.25%, 3.125%, 1.57%, 0.78%. results seen calculating colonies Mueller Hinton Agar (MHA). Kruskal-Wallis test performed analyze data statistically. Results: There significant differences each treatment group (p<0.05), inhibitory beginning concentration 3.125%. Conclusion: (Eichhornia crassipes) inhibits MIC90 3.125% an MBC99,9 6.25%.